Male lower urinary tract symptoms in correlation with age, quality of life scores, parameters of uroflowmetry and prostate size, a single institution study

OBJECTIVE@#To correlate male lower urinary tract symptoms between age, quality of life scores,parameters of uroflowmetry and prostate size.@*PATIENTS AND METHODS@#Two hundred eight males were included in this study. Uroflowmetry parameters,age, International Prostate Symptom Score (IPSS), Quality of Life (QoL) scores and prostate sizewere gathered. For correlation, distribution of age, uroflowmetry parameters and prostate size werefirst compared to IPSS. Analysis of variance was used to compare age of patients, while Kruskall-wallis test was used to compare the QoL, uroflowmetry parameters, and prostate size on each IPSSgroups. Ordinal logistic regression analysis was used to correlate IPSS to age, quality of life,uroflowmetry parameters, and prostate size both for multivariate and univariate analysis.@*RESULTS@#There was no significant correlation between age and IPSS. However, on profile distribution,the age distribution between symptom scores were statistically similar. Qol scores were directlyproportional to IPSS. Thus, patients with a worse QoL score were more likely to have higher IPSS.Qmax scores decreased as symptom severity increased. Patients with higher Qmax scores are lesslikely to have higher IPSS scores. Voided volume was observed to decrease as IPSS severity increased,but this was not statistically significant. Patients with higher post void residual scores were morelikely to have higher IPSS. There was also no significant correlation between prostate size and IPSS.@*CONCLUSION@#There were no significant correlation between IPSS and age, voided volume and prostatesize. On the other hand, patients with a worse QoL score and a high post void residual had higherIPSS. Patients with a high Qmax, are less likely to have an elevated IPSS.

5-alpha reductase inhibitor: a new therapeutic option in the treatment of benign prostatic hypertrophy

A placebo-controlled randomized study of 60 patients over 50 years was undertaken to measure the effectiveness of finasteride in the management of BPH. Significant changes in the uterine flow rate, PSA level, mass volume and symptom severity score were noted.